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  1. ATS 2026 XTMAB-16 in Sarcoidosis: First-in-Patient Study Results

    Dr. Ogugua N. Obi, Director of the Sarcoidosis Center of Excellence at ECU, presented the latest update on XTMAB-16 in …

  2. XTMAB-16 - Xentria

    The story of XTMAB-16 is one of trust, collaboration, expertise and tenacity combining to create an outcome that matched the …

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  3. Study Details | NCT07680166 | A Seamless, Adaptive Multiple …

    Jul 2, 2026 · A Seamless, Adaptive Multiple-Ascending-Dose and Efficacy Study of XTMAB-16 in Patients with Pulmonary …

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  4. XTMAB-16

    XTMAB-16 is a chimeric human-murine IgG1k anti-TNFa monoclonal antibody with a molecular weight of ~149 kDa being developed …

  5. XTMAB16 Study: A Phase 2, Randomized, Double-blind Clinical Trial ...

    May 1, 2025 · Results Part A will evaluate the safety and tolerability of multiple-ascending doses of XTMAB-16 in 32 participants with …

  6. Study Details | NCT06169397 | An Open-label Extension Study of XTMAB-16 ...

    Dec 13, 2023 · Evidence of treatment-related AEs requiring treatment discontinuation per XTMAB-16-201 protocol observed in …

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  7. Characterization studies were performed on XTMAB-16 drug substance batches produced in the commercial scale. Results include …

  8. A phase 1b/2 study of XTMAB-16 in patients with pulmonary sarcoidosis

    The aim of this study is to examine how well XTAMB-16 helps improve sarcoidosis by measuring the participants’ use of oral …

  9. Safety, Tolerability, and Pharmacokinetics of a Single Intravenous ...

    Mar 25, 2025 · This is a single-center, randomized, double-blind, placebo-controlled, first-in-human, single intravenous (IV) infusion …

  10. XTMAB-16 - Drug Targets, Indications, Patents - Synapse

    May 16, 2026 · XTMAB-16 is a chimeric anti-tumor necrosis factor alpha (TNFα) antibody, distinct from other anti-TNF antibodies …