-
Kizdar net |
Kizdar net |
Кыздар Нет
Two-input protein logic gate for computation in living cells
Nov 16, 2021 · Our study provides proof-of-principle that a single protein can be programmed as a logic gate by allosteric wiring of two inputs to a functional site, which serves as an output.
- Author: Yashavantha L. Vishweshwaraiah, Jiaxing Chen, Venkat R. Chirasani, Erdem D. Tabdanov, Nikolay V. Dok...
- Publish Year: 2021
Genetic programs constructed from layered logic gates in ... - Nature
Oct 7, 2012 · We have designed a transcriptional 2-input AND gate, in which one input promoter drives the expression of an activator and the second input promoter drives the expression of a …
- Author: Tae Seok Moon, Chunbo Lou, Alvin Tamsir, Brynne Christine Stanton, Christopher A. Voigt
- Publish Year: 2012
When de novo-designed protein logics meet CAR-T therapies
Sep 25, 2020 · In a recent paper published in Science, Lajoie et al. engineered highly versatile colocalization-dependent protein switch that are activated upon detection of logic …
- Author: Mingqi Xie, Peilong Lu
- Publish Year: 2020
Searches you might like
A Biological OR(XNOR) Logic Gate Couples Carbon Source and …
We constructed a three-input biological logic gate: S OR (G XNOR M), where S is sorbitol, G is glycerol, and M is methanol, to optimize co-expression of two transgenes in Komagataella …
Controlling gene expression with computer-inspired …
Apr 7, 2020 · Scientists have designed tools to regulate protein-protein interactions, akin to the structure of electronics, that are capable of controlling …
- Estimated Reading Time: 3 mins
De novo design of protein logic gates - PMC - National Center for ...
Apr 3, 2020 · The design of modular protein logic for regulating protein function at the post-transcriptional level is a challenge for synthetic biology. Here we describe the design of 2-input …
- People also ask
A Biological OR(XNOR) Logic Gate Couples Carbon …
Feb 27, 2023 · We constructed a three-input biological logic gate: S OR (G XNOR M), where S is sorbitol, G is glycerol, and M is methanol, to optimize co-expression of two transgenes in Komagataella phaffii using batch-mode …
Design and characterisation of biological XOR gates.
The logic gate can integrate multiple input signals following a set of algorithms and generate a response only if strictly defined conditions are met.
Amplifying Genetic Logic Gates | Science - AAAS
Mar 28, 2013 · We realized permanent amplifying AND, NAND, OR, XOR, NOR, and XNOR gates actuated across common control signal ranges and sequential logic supporting autonomous cell-cell communication of DNA encoding distinct …
De novo design of protein logic gates - PubMed
Apr 3, 2020 · The design of modular protein logic for regulating protein function at the posttranscriptional level is a challenge for synthetic biology. Here, we describe the design of …
These Protein Logic Gates Turn Cells Into Computers
Scientists created protein logic gates that shape human biology like computer tools, hinting at the future of medicine. The tools we use to make computers work are now seeing new applications —...
Microsoft Copilot: Your AI companion
Microsoft Copilot is your companion to inform, entertain, and inspire. Get advice, feedback, and straightforward answers. Try Copilot now.
The Cystine/Glutamate Antiporter System x
Protein kinase C (PKC) is activated by G q-coupled receptors via phospholipase C and diacylglycerol.
Designing protein logic gates - Nature Methods
Jun 4, 2020 · De novo–designed protein logic gates allow post-translational regulation of protein function. Cellular function can be controlled by regulating protein–protein association; …
System xc- cystine/glutamate antiporter: an update on molecular ...
System x c- (Sx C-) is an amino acid antiporter that typically mediates the exchange of extracellular l -cystine (l -Cys 2) and intracellular l -glutamate (l -Glu) across the cellular …
GATE-16, a membrane transport modulator, interacts with NSF …
We propose that the GATE–16 protein family has a pleiotropic effect, acting as chaperones for membrane proteins that undergo functional conformational changes.
Membrane protein insertion through a mitochondrial β-barrel gate
Jan 18, 2018 · Making your way through the side of a barrel The mechanism of membrane insertion and assembly of b-barrel proteins is a central question of outer membrane biogenesis …
Molecular basis for redox control by the human cystine ... - Nature
Dec 8, 2021 · Cystine functions to coordinate the mobile gate helices, TM1 and 6 with the hash domain. Specifically, Arg135 on TM3 and Arg396 on TM10, which pull Tyr244 on TM6A to seal …
Skip to content
