Bacterial type IV secretion systems (T4SSs) are a versatile group of nanomachines that can horizontally transfer DNA through conjugation and deliver effector proteins into a wide range of …

Oct 9, 2023 · Various pathogenic bacteria and symbionts deploy type IV secretion systems (T4SSs) to deliver effector proteins, DNA–protein complexes or other macromolecules into …

Bacteria use type IV secretion systems for two fundamental objectives related to pathogenesis — genetic exchange and the delivery of effector molecules to eukaryotic target cells.

Aug 1, 2014 · The bacterial type IV secretion systems (T4SSs) translocate DNA and protein substrates to bacterial or eukaryotic target cells generally by a mechanism dependent on …

Type IV secretion systems (T4SSs) are versatile secretion systems that are found in both Gram-negative and Gram-positive bacteria and secrete a wide range of substrates, from single …

Together, these recent findings describe the mechanics of type IV secretion in unprecedented detail. The bacterial type IV secretion systems (T4SS) comprise a large family of translocation …

Type IV secretion systems (T4SSs) are large multisubunit translocons, found in both gram-negative and gram-positive bacteria and in some archaea. These systems transport a diverse …

Type IV secretion systems (T4SSs) are specialized macromolecule delivery machines ancestrally related to bacterial conjugation systems.

Nov 1, 2003 · Bacteria use type IV secretion systems for two fundamental objectives related to pathogenesis — genetic exchange and the delivery of effector molecules to eukaryotic target …

In this Review, we aim to summarize these exciting structural and molecular biology findings and to discuss their functional implications for substrate recognition, recruitment and translocation, …

Feb 5, 2025 · Type IV pili (T4P) machinery is critical for bacterial surface motility, protein secretion, and DNA uptake. This review highlights the ecological significance of T4P …

Type IV secretion (T4S) systems are ancestrally related to bacterial conjugation machines. These systems assemble as a translocation channel, and often also as a surface filament or protein …

Type IV secretion systems (T4SSs) are multisubunit cell-envelope-spanning structures, ancestrally related to bacterial conjugation machines, which transfer proteins and …

Mar 18, 2025 · Plasmid pKP114-NDM was observed to harbor relaxase, type IV coupling protein (T4CP), and type IV secretion system (T4SS), indicating a potential horizontal transmission of …

Aug 11, 2022 · Bacterial type IV secretion systems (T4SSs) are a versatile group of nanomachines that can horizontally transfer DNA through conjugation and deliver effector …

4 days ago · Introduction. Bacteriophages – also known as phages – are viruses that infect bacteria. They are ubiquitous in the environment and significantly outnumber their bacterial …

Bacteria use type IV secretion systems for two fundamental objectives related to pathogenesis — genetic exchange and the delivery of effector molecules to eukaryotic target cells.

Bacteria are microscopic, single-celled organisms classified as prokaryotes, meaning they lack membrane-bound organelles, such as nuclei. Their classification system, rooted in the work of …

Type IV secretion systems (T4SSs) are versatile secretion systems that are found in both Gram-negative and Gram-positive bacteria and secrete a wide range of substrates, from single …

In Gram-negative bacteria, type IV secretion (T4S) systems form ATP-powered complexes that span the entire cellular envelope and secrete a wide variety of substrates from single proteins …

Mar 21, 2025 · Most infections were caused by species in the Enterobacterales order (3385 of 3729 [90.8%]), with one trial focused only on Enterobacterales bloodstream infection 3 and the …

Type IV secretion (T4S) systems are ancestrally related to bacterial conjugation machines. These systems assemble as a translocation channel, and often also as a surface filament or protein …