In the episode "The Herb Garden Germination", he became engaged to Bernadette when she accepted his marriage proposal. They eventually married in the season 5 finale, "The Countdown Reflection", which featured a small reception.

Bernadette is Howard's wife and one of the main characters on the television show The Big Bang Theory. This character is spunky, driven, intelligent, and knows what she wants in life. Bernadette can be sweet and supportive, but she also isn't afraid to force her partner to face reality.