Below is a list of the cast of The Big Bang Theory and the real people they call their significant other. Jim Parsons starred as theoretical physicist Sheldon Cooper and throughout the show had a romantic relationship with Mayim Bialik's character Amy Fowler.

1- The real-life relationships of The Big Bang Theory cast reveal love stories beyond the screen. 2- Jim Parsons, Kaley Cuoco, and Johnny Galecki all have unique romantic partnerships off-screen. 3- From marriages to new loves, the cast members have personal lives that differ from their on-screen personas.

"The Big Bang Theory" was a wildly popular CBS sitcom running for 12 seasons. The show followed a group of socially awkward scientists, including the roommates at the core of the show: Sheldon Cooper (played by Jim Parsons) and Leonard Hofstadter (played by Johnny Galecki).

Parson's actual wedding day came days after his on-screen proposal to Bialik's character in "The Big Bang Theory." His costar and fictional fiancée spoke about attending the wedding, telling KTLA 5, "It was gorgeous. It was a very intimate, beautiful event." In addition to their romantic relationship, Spiewak and Parsons have worked together.