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  1. Seneca Valley virus disease is a viral vesicular disease of pigs caused by a picornavirus related to the viruses that cause foot-and-mouth disease and swine vesicular disease. Clinically affected pigs develop cutaneous vesicular lesions, mainly on the snout and coronary bands.

    Seneca Valley Virus Disease in Pigs - Merck Veterinary Manual

    www.merckvetmanual.com/generalized-conditions/seneca-valley-virus-disease/seneca-valley-virus-disease-in-pigs
    www.merckvetmanual.com/generalized-conditions/seneca-valley-virus-disease/…
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    Are senecaviruses associated with porcine vesicular disease?
    The first evidence that senecaviruses could be associated with porcine vesicular disease was obtained in Canada (2008) and the USA (2012), where symptomatic pigs were detected with the viral RNA by reverse transcription (RT)-PCR assay [ 11, 12 ].

    Update on Senecavirus Infection in Pigs - PMC - National Center for

    ncbi.nlm.nih.gov
    Does vesicular disease affect pigs?
    SVA was found in lesions in pigs affected by porcine idiopathic vesicular disease in Canada and the USA in 2008 and 2012, respectively. In 2014 and 2015, SVA infection was associated with outbreaks of vesicular disease in sows as well as neonatal pig mortality in Brazil and the USA.

    Senecavirus A: An Emerging Pathogen Causing Vesicular Disease and

    journals.sagepub.com
    Can RNA-based in situ hybridization detect Seneca Valley virus in neonatal piglets?
    A novel RNA-based in situ hybridization to detect Seneca Valley virus in neonatal piglets and sows affected with vesicular disease. PLoS One. 2017;12(4):e0173190. [ PMC free article] [ PubMed] [ Google Scholar] 37. Hause BM, Myers O, Duff J, Hesse RA. Senecavirus A in pigs, United States, 2015. Emerg Infect Dis. 2016;22(7):1323–1325.

    Prevalence of Senecavirus A in pigs from 2014 to 2020: a global

    ncbi.nlm.nih.gov
    Is SVA endemic in pigs?
    The possibility of SVA’s being a potentially endemic virus in some pig populations or causing subclinical infections cannot be ruled out at present. Moreover, SVA has also been detected in environmental samples as well as mice and houseflies present in affected and nonaffected pig farms, 18 further emphasizing the likelihood of endemicity.

    Senecavirus A: An Emerging Pathogen Causing Vesicular Disease and

    journals.sagepub.com
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  3. Merck Veterinary Manual
    https://www.merckvetmanual.com/generalized...

    Seneca Valley Virus Disease in Pigs - Merck Veterinary Manual

     
  4. Veterinary Diagnostic Lab
    https://vdl.umn.edu/resources/disease-resources/...

    Senecavirus A - SVA (Seneca Valley Virus) - Veterinary …

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  5. Studies of senecavirus a in pigs
    Update on Senecavirus Infection in Pigs
    Senecavirus A (SVA) is a positive-sense single-stranded RNA virus that belongs to the Senecavirus genus within the Picornaviridae family. The virus has been silently circulating in pig herds of the USA since 1988. However, cases of senecavirus-associated
    Author: Raquel A Leme
    Published: 2017/07/03
    Keywords: Seneca Valley virus; emergent disease; neonatal mortality; picornavirus; swine; vesicular disease
    PubMed
    Prevalence of Senecavirus A in pigs from 2014 to 2020: a global systematic review and meta-analysis
    Background: Senecavirus A (SVA), a member of the family Picornaviridae, is newly discovered, which causes vesicular lesions, lameness in swine, and even death in neonatal piglets. SVA has rapidly spread worldwide in recent years, especially in Asia.
    Author: Xuhua Ran
    Published: 2023/5
    Keywords: Senecavirus A (SVA), a member of the family Picornaviridae, is newly discovered, which causes vesicular lesions, lameness in swine, and even death in neonatal piglets. SVA has rapidly spread worldwide in recent years, especially in Asia
    PubMed
    Prevalence of Senecavirus A in pigs from 2014 to 2020: a global systematic review and meta-analysis
    Background Senecavirus A (SVA), a member of the family Picornaviridae, is newly discovered, which causes vesicular lesions, lameness in swine, and even death in neonatal piglets. SVA has rapidly spread worldwide in recent years, especially in Asia.
    Author: Xuhua Ran, Zhenru Hu, Jun Wang, Zhiyuan Yang, Zhongle Li, Xiaobo Wen
    Published: 2023/05
    Publication: J Vet Sci. 2023 May; 24(3): e48.
    National Center for Biotechnology Information
    Update on Senecavirus Infection in Pigs
    Senecavirus A (SVA) is a positive-sense single-stranded RNA virus that belongs to the Senecavirus genus within the Picornaviridae family. The virus has been silently circulating in pig herds of the USA since 1988. However, cases of senecavirus-associated
    Author: Raquel A. Leme, Alice F. Alfieri, Amauri A. Alfieri
    Published: 2017/07
    Publication: Viruses. 2017 Jul; 9(7): 170.
    National Center for Biotechnology Information
    Pathogenicity of Seneca Valley virus in pigs and detection in Culicoides from an infected pig farm
    Background Porcine vesicular disease is caused by the Seneca Valley virus (SVV), it is a novel Picornaviridae, which is prevalent in several countries. However, the pathogenicity of SVV on 5–6 week old pigs and the transmission routes of SVV remain
    Author: Jinyong Zhang, Chenghui Li, Yuan Meng, Yubiao Xie, Ning Shi, He Zhang, Chengdong Yu, Fulong Nan, Changzhan Xie, Zhuo Ha
    Published: 2021
    Publication: Virol J. 2021; 18: 209.
    National Center for Biotechnology Information
    Senecavirus A seroprevalence and risk factors in United States pig farms
    Senecavirus A (SVA) is a non-enveloped, single-stranded, positive-sense RNA virus belonging to the Picornaviridae family. Senecavirus A is constantly associated with outbreaks of vesicular disease in pigs and has been reported in several countries
    Author: Guilherme Preis
    Published: 2022/10/20
    Keywords: risk factors; senecavirus A; seroprevalence; swine; vesicular disease
    PubMed
    Adaptive Immune Responses following Senecavirus A Infection in Pigs
    Senecavirus A (SVA), an emerging picornavirus of swine, causes vesicular disease (VD) that is clinically indistinguishable from foot-and-mouth disease (FMD) in pigs. Many aspects of SVA interactions with the host and the host immune responses to infection,
    Author: Mayara F Maggioli
    Published: 2018/01/17
    Keywords: SVA; SVV; Seneca Valley virus; vesicular disease; virus-host interactions
    PubMed
    Detection of the Emerging Picornavirus Senecavirus A in Pigs, Mice, and Houseflies
    Senecavirus A (SVA) is an emerging picornavirus that has been recently associated with an increased number of outbreaks of vesicular disease and neonatal mortality in swine. Many aspects of SVA infection biology and epidemiology remain unknown.
    Author: Lok R Joshi
    Published: 2016/6
    Keywords: National Institutes of Health; National Center for Biotechnology Information; National Library of Medicine; MEDLINE;
    PubMed
    Detection of the Emerging Picornavirus Senecavirus A in Pigs, Mice, and Houseflies
    Senecavirus A (SVA) is an emerging picornavirus that has been recently associated with an increased number of outbreaks of vesicular disease and neonatal mortality in swine. Many aspects of SVA infection biology and epidemiology remain unknown.
    Author: Lok R. Joshi, Kristin A. Mohr, Travis Clement, Kyle S. Hain, Bryan Myers, Joseph Yaros, Eric A. Nelson, Jane Christopher-Hennings, Danielle Gava, Rejane Schaefer
    Published: 2016/06
    Publication: J Clin Microbiol. 2016 Jun; 54(6): 1536–1545.
    National Center for Biotechnology Information
    Pathogenesis of Senecavirus A infection in finishing pigs
    Senecavirus A (SVA) is an emerging picornavirus that has been associated with vesicular disease and neonatal mortality in swine. Many aspects of SVA infection biology and pathogenesis, however, remain unknown. Here the pathogenesis of SVA was investigated
    Author: Lok R Joshi
    Published: 2016/12
    Keywords: National Institutes of Health; National Center for Biotechnology Information; National Library of Medicine; MEDLINE;
    PubMed
  6. PubMed
    https://pubmed.ncbi.nlm.nih.gov/28671611

    Update on Senecavirus Infection in Pigs - PubMed

  7. PubMed
    https://pubmed.ncbi.nlm.nih.gov/37271515

    Prevalence of Senecavirus A in pigs from 2014 to 2020: a global ...

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  8. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244137

    Prevalence of Senecavirus A in pigs from 2014 to 2020: a global ...

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    10.4142/jvs.22307
  9. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537662

    Update on Senecavirus Infection in Pigs - PMC - National Center …

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    Publish Year:2017
    Senecavirus Infection in Pigs
    Viruses. 2017 Jul; 9(7): 170.
  10. Frontiers
    https://www.frontiersin.org/journals/veterinary...

    Senecavirus A seroprevalence and risk factors in United States …

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  11. MDPI
    https://www.mdpi.com/1999-4915/9/7/170

    Viruses | Free Full-Text | Update on Senecavirus …

    WEBJul 3, 2017 · Senecavirus A (SVA) is a positive-sense single-stranded RNA virus that belongs to the Senecavirus genus within the Picornaviridae family. The virus has been silently circulating in pig herds of the USA …

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    Publish Year:2017
    Senecavirus Proteins
  12. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8529370

    Pathogenicity of Seneca Valley virus in pigs and detection in

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    Senecavirus Infection of Bovine Cattle
  13. PubMed
    https://pubmed.ncbi.nlm.nih.gov/36337199

    Senecavirus A seroprevalence and risk factors in United States …

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  14. Swine Health Information Center
    https://www.swinehealth.org/seneca-va…

    Senecavirus A Summary – Swine Health Information …

    WEBSenecavirus A (SVA) is a small, non-enveloped picornavirus, unknown until 2002 when it was discovered incidentally as a cell culture contaminant. Only a single species is classified in the genus Senecavirus. The family …

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  15. Centers for Disease Control and Prevention
    https://wwwnc.cdc.gov/eid/article/22/7/15-1591

    Senecavirus A in Pigs, United States, 2015 - Volume 22, Number …

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  16. SAGE Journals
    https://journals.sagepub.com/doi/10.1177/0300985816653990

    Senecavirus A: An Emerging Pathogen Causing Vesicular …

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    Senecavirus A in Pigs
    Publish Year:2017
  17. Centers for Disease Control and Prevention
    https://wwwnc.cdc.gov/eid/article/22/7/15-1863

    Vesicular Disease in 9-Week-Old Pigs Experimentally Infected …

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  18. Frontiers
    https://www.frontiersin.org/journals/veterinary...

    Epidemiological investigation of Senecavirus A infection in pig …

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  19. Veterinary Diagnostic Laboratory
    https://vetmed.iastate.edu/.../pathogens/senecavirus

    Senecavirus A | Iowa State University

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  20. PubMed
    https://pubmed.ncbi.nlm.nih.gov/29142122

    Adaptive Immune Responses following Senecavirus A Infection in …

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  21. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918151

    Senecavirus A in Pigs, United States, 2015 - PMC - National …

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    Publish Year:2016
  22. American Association of Swine Veterinarians
    https://www.aasv.org/shap/issues/v30n3/v30n3p149.pdf
    [PDF]

    Senecavirus A: Frequently asked questions - AASV

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  23. Centers for Disease Control and Prevention
    https://wwwnc.cdc.gov/eid/article/22/7/pdfs/15-1591.pdf
    [PDF]

    Senecavirus A in Pigs, United States, 2015 - Centers for …

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  24. PubMed
    https://pubmed.ncbi.nlm.nih.gov/27030489

    Detection of the Emerging Picornavirus Senecavirus A in Pigs

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  25. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879313

    Detection of the Emerging Picornavirus Senecavirus A in Pigs, …

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    Publish Year:2016
  26. PubMed
    https://pubmed.ncbi.nlm.nih.gov/27902357

    Pathogenesis of Senecavirus A infection in finishing pigs

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