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- Studies of seneca valley virus treatment
Seneca Valley Virus Disease in Pigs
WEBTreatment, Control, and Prevention |. Key Points |. References. Seneca Valley virus disease is a viral vesicular disease of pigs caused by a picornavirus related to the viruses that cause foot-and-mouth disease and swine vesicular disease. Clinically affected pigs …
WEBIn the laboratory, an accelerated hydrogen peroxide-based disinfectant (Prevail® concentrate, Virox Technologies, Inc.) is also effective against SVA when applied at …
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Review of Seneca Valley Virus: A Call for Increased Surveillance …
WEBSeneca Valley virus infection develops a rapid neutralizing antibody (NA) response in sows and finishing pigs regardless of the clinical manifestations of the disease (Gimenez …
- Author: Xiangle Zhang, Zixiang Zhu, Fan Yang, Weijun Cao, Hong Tian, Keshan Zhang, Haixue Zheng, Xiangtao Li...
- DOI: 10.3389/fmicb.2018.00940
- Publish Year: 2018
- Publication: Front Microbiol. 2018; 9: 940.
Senecavirus A as an Oncolytic Virus: Prospects, Challenges and ...
WEBSeneca Valley Virus 3C Protease Negatively Regulates the Type I Interferon Pathway by Acting as a Viral Deubiquitinase. Antiviral Res (2018) 160:183–9. doi: …
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SENECA VALLEY VIRUS
WEBDetectable levels of infectious virus have been found in nasal secretions, sputum, blood, urine, and stool in human cancer patients treated with intravenous SVV-001 in clinical …
Seneca Valley Virus, a Systemically Deliverable Oncolytic …
WEBWe determined the cytolytic potential and selectivity of Seneca Valley Virus-001 (SVV-001), a newly discovered native picornavirus, in neuroendocrine and pediatric tumor cell lines …
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Seneca Valley virus, a systemically deliverable oncolytic …
WEBSystemically administered SVV-001 has potential for the treatment of metastatic neuroendocrine cancers. SVV-001 has potent cytolytic activity and high selectivity for …
A Randomized Double-Blind Phase II Study of the Seneca Valley …
WEBIntroduction: The Seneca Valley virus (NTX-010) is an oncolytic picornavirus with tropism for SCLC. This phase II double-blind, placebo-controlled trial evaluated NTX-010 in …
Seneca Valley Virus
WEBSeneca Valley Virus (SVV) is a disease circulating in pigs. The clinical signs associated with SVV in pigs include vesicles (blisters) or erosions (results of ruptured vesicles) on a pig’s snout, mouth, or feet where the …
725. Seneca Valley Virus, a Novel Systemically Deliverable …
WEBWhile conceptually attractive, key hurdles remain before an oncolytic virus can be systemically administered both effectively and safely, the basis for a successful …
Frontiers
WEBSeneca Valley virus infection develops a rapid neutralizing antibody (NA) response in sows and finishing pigs regardless of the clinical manifestations of the disease (Gimenez …
Structural basis for anthrax toxin receptor 1 recognition by Seneca ...
WEBRecently, ANTXR1 was identified as the high-affinity cellular receptor for Seneca Valley Virus (SVV). SVV has shown promising results as an oncolytic agent in clinical trials, …
Persistent Infection and Transmission of Senecavirus A from …
WEBImportantly, persistently infected carrier animals shedding SVA in oral and nasal secretions or feces can serve as sources of infection to other susceptible animals, as evidenced …
Senecavirus A
WEBBackground. Senecavirus A is a non‐enveloped single‐stranded RNA virus of the family Picronaviradae. Foot and Mouth. Disease Virus (FMDV) and swine vesicular disease …
291. In Vivo Characterization of Seneca Valley Virus (SVV-001), a …
WEBSeneca Valley Virus (SVV-001) is a novel native picornavirus being developed as a systemically deliverable oncolytic virus for treatment of human cancers with …
Seneca Valley virus enters cells through multiple pathways and ...
WEBThen, we discovered that chlorpromazine (CPZ) treatment or knockdown of the clathrin heavy chain (CLTC) protein significantly inhibited SVV infection. In addition, …
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SENECA VALLEY VIRUS
WEBImmunity. Serological studies have revealed the natural occurrence of neutralizing anti-SVV antibodies in swine, cattle, and mice, but rarely in humans. Both humans and mice have …
Seneca Valley Virus - an overview
WEBPicornaviridae. In Fenner's Veterinary Virology (Fifth Edition), 2017. SENECA VALLEY VIRUS. Seneca Valley virus is the sole member of the genus Senecavirus. It was first …
Evolving role of seneca valley virus and its biomarker …
WEBIn this review we will discuss one such promising oncolytic virus called Seneca Valley Virus (SVV-001) and its therapeutic implications. SVV development has seen seismic …
Cancer-Killing Virus Shows Promise as Metastatic Cancer …
WEBThe virus may be a potential treatment for some metastatic cancers, such as small-cell lung cancer. Cancer-killing viruses have been shown in clinical trials to be promising …
A randomized double-blind phase II study of the Seneca Valley …
WEBThe Seneca Valley Virus (NTX-010) is an oncolytic picornavirus with tropism for small cell lung cancer (SCLC). This phase II double-blind, placebo controlled trial evaluated NTX …
West Nile Virus Detected in Salt Lake County - Health Department
WEBThere is no specific treatment for WNV infection other than to treat symptoms. If you think you have WNV infection, contact your health care provider. WNV was first detected in …
Phase I clinical study of Seneca Valley Virus (SVV-001), a ...
WEBPMCID: PMC5317273. DOI: 10.1158/1078-0432.CCR-10-1706. Abstract. Purpose: Seneca Valley Virus (SVV-001) is a novel naturally occurring replication-competent picornavirus …
A 5-Year Review of Senecavirus A in China since Its Emergence …
WEBSenecavirus A (SVA), previously known as Seneca Valley virus, is classified into the genus Senecavirus in the family Picornaviridae. This virus can cause vesicular disease and …
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