Jul 14, 2025 · Specific questions that were addressed included the mechanisms by which these cytokines influence immune responses and their potential roles in infectious diseases, …

Frontiers in Immunology (Jul 2025) Editorial: The role of TGF-beta superfamily members in immune homeostasis and disease Natalie Eva Nieuwenhuizen, Ioannis Eleftherianos, Piotr …

Oct 27, 2020 · Dysregulation of the TGF-β superfamily signaling is implicated in various human diseases including cancer, fibrosis, autoimmune diseases and vascular disorders, although the …

More than twenty presentations and discussions at the symposium delved into the intricate mechanisms of TGF-β superfamily signaling pathways, their roles in normal development and …

Dec 7, 2018 · Although the effects of these factors on immune responses were elucidated long ago, most studies have been focused on the actions of TGFβs on T cells, as major regulators …

Jan 1, 2021 · It is implicated throughout development and adulthood in immune regulation, metabolism and homeostasis, through to fibrosis and wound repair (David & Massague, 2018). …

Apr 16, 2019 · TGF-β is also central to immune suppression within the tumor microenvironment, and recent studies have revealed roles in tumor immune evasion and poor responses to …

Nov 25, 2016 · In this Review, the authors discuss the emerging roles for members of the transforming growth factor-β (TGFβ) superfamily in regulating immune responses.

Jun 27, 2025 · The TGF-beta superfamily, encompassing molecules such as TGFs, activins, BMPs, GDFs, and Nodals, represents the largest family of growth and differentiation factors, …

Jan 1, 2010 · This review summarizes the progresses that have been accomplished on the understanding of TGF-β’s signaling in the immune homeostasis and its role in pathogenesis.