When while is the first word of your sentence, you obviously shouldn’t add a comma in front of it. But if you’re using while to mean “whereas,” you still need to put a comma somewhere. Put it at the end of the clause that while introduces. The comma should go between the things being contrasted or happening at the same time.

When the first word of your sentence is ‘while’ you should not put a comma in front of it. However, if you use while to mean ‘whereas’ you must include a comma somewhere. Put it at the end of the clause that has been introduced by while. The comma should be placed between the two things that are being compared or occurring at the same time.

When the “while” clause appears at the start of the sentence, there should be a comma at the end of the clause (not next to the word “while” itself). This applies regardless of whether “while” is used to mean “during the time that” or “whereas.” This comma should always be added.

Using a comma before “while” can change the meaning of a sentence. When “while” is used to mean “although” or “whereas,” a comma is typically necessary. However, when “while” is used to indicate a period of time, a comma is usually not needed.

While is a conjunction that can be used to indicate time or contrast. When while is used to indicate time, it does not require a comma. However, when while is used to indicate contrast, a comma is necessary. For example: I will go to the gym while you work. (No comma because while is used to indicate time)