Tasmanian Devil Disease - Search
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  1. Devil facial tumour diseaseClonally transmissible cancer
    OverviewSymptomsCausesDiagnosisTreatmentsRisk factorsPrevalence
  2. Clinical signs

    There is often more than one primary tumour. Visible signs of DFTD begin with lumps of soft tissue around the mouth, which ulcerate. Tumours are locally aggressive, destroying the underlying bone of the jaw … See more

    Transmission

    The most plausible route of transmission is through biting, particularly when canine teeth come into direct contact with the diseased cells. Other modes of transmission may include the ingestion of infected car… See more

    Pathology

    DFTD tumours are large soft tissue masses which become centrally ulcerated. The tumours are composed of lobules of nodules of round to spindle-shaped cells, often within a pseudocapsule. Tumours metastasise to … See more

    Tumour characteristics

    Tasmanian devil cells have 14 chromosomes; the oldest-known strain of the tumour cells have thirteen chromosomes, nine of which are recognisable and four of which are mutated "marker" ch… See more

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