Human hair serves a variety of purposes. These include physical protection, thermal insulation, dispersion of sweat and sebum, as well as sensory and tactile functions. Human hair also plays a role in social interactions. The hair follicle is considered a mini-organ and forms from ectodermal hair fo...

Hair follicle morphogenesis depends on Wnt, Shh, Notch, BMP and other signaling pathways interplay between epithelial and mesenchymal cells. The Wnt pathway plays an essential role during hair follicle induction, Shh is involved in morphogenesis and late stage differentiation, Notch signaling determ...

The mammalian hair follicle arises during embryonic development from coordinated interactions between the epidermis and dermis. It is currently unclear how to recapitulate hair follicle induction in pluripotent stem cell cultures for use in basic research studies or in vitro drug testing. To date, g...

Hair follicle is an appendage from the vertebrate skin epithelium, and is critical for environmental sensing, animal appearance, and body heat maintenance. Hair follicles arise from the embryonic ectoderm and regenerate cyclically during adult life. Distinct morphological and functional stages from ...

Background: SiFAr-Stress investigates the impact of cycling on stress levels in older adults. Uncertainty due to change to motorized bicycle or fear of falling can be perceived as stressors for cyclists. Stress activates different physiological signal cascades and stimulates the hypothalamic-pituita...