AAT Deficiency - Search
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  1. Alpha-1 antitrypsin deficiency
    Alpha-1 antitrypsin deficiencyGenetic disorder
    SymptomsCausesDiagnosisTreatmentsClinical trialsRisk factorsPrevalence
     
  2. Cleveland Clinic
    https://my.clevelandclinic.org › health › diseases

    Alpha-1 Antitrypsin Deficiency: Causes, Symptoms & Treatment

    • Alpha-1 is a genetic disorder that lowers the protein that protects your lungs from damage. Learn about the symptoms, diagnosis and treatment options for this condition that can cause emphysema, cirrhosis a… See more

    How Is Alpha-1 Treated?

    For those with lung conditions from Alpha-1, your provider can treat you with COPD … See more

    Cleveland Clinic
    What Medications/Treatments Are used?

    Depending on where Alpha-1 affects you, treatment options may include: 1. Augmentation therapy.Your provider can increase your AAT levels by giving you supplement… See more

    Cleveland Clinic
    What Can’T I Eat/Drink with Alpha-1?

    You should avoid alcohol if you have certain types of Alpha-1 or are a carrier. Alcohol can increase your chances of liver damage. You should also avoid medication… See more

    Cleveland Clinic
    Alpha-1 antitrypsin deficiency - Wikipedia
    A genetic disorder that causes lung or liver disease due to low levels of alpha-1 antitrypsin protein. Learn about the symptoms, causes, diagnosis, treatment, and prognosis of this conditi…
    Wikipedia · https://en.wikipedia.org/wiki/Alph…
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    How Is Alpha-1 Treated?
    What Medications/Treatments Are used?
    What Can’T I Eat/Drink with Alpha-1?
     
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  1. Alpha-1 antitrypsin
    • According to 2 sources
    Alpha-1 antitrypsin (AAT) deficiency is a condition that can cause serious lung or liver disease. Symptoms often include trouble breathing and jaundiced, or yellow, skin. It's a genetic disease, which means it's passed down to you from your parents.

    Alpha-1 Antitrypsin (AAT) D…

    webmd.com
    Alpha-1 antitrypsin (AAT) deficiency is a condition in which the body does not make enough of AAT, a protein that protects the lungs and liver from damage. The condition can lead to chronic obstructive pulmonary disease (COPD) and liver disease (cirrhosis).

    Alpha-1 Antitrypsin Deficien…

    pennmedicine.org
     
  2. Wikipedia
    https://en.wikipedia.org › wiki

    Alpha-1 antitrypsin deficiency - Wikipedia

    A genetic disorder that causes lung or liver disease due to low levels of alpha-1 antitrypsin protein. Learn about the symptoms, causes, diagnosis, treatment, and prognosis of this condition.

     
  3. NHLBI, NIH
    https://www.nhlbi.nih.gov › health

    COPD - Alpha-1 Antitrypsin Deficiency - NHLBI, NIH

    Oct 25, 2023 · Learn about AAT deficiency, a genetic condition that raises the risk for lung and liver diseases. Find out how it is inherited, diagnosed, and treated, and how it can cause COPD or bronchiectasis.

  4. WebMD
    https://www.webmd.com › lung › copd

    Alpha-1 Antitrypsin (AAT) Deficiency - WebMD

    Dec 13, 2023 · Alpha-1 antitrypsin (AAT) deficiency is a condition that can cause serious lung or liver disease. Symptoms often include trouble breathing and jaundiced, or yellow, skin. It's a genetic...

  5. Penn Medicine
    https://www.pennmedicine.org › ... › conditions-treated-a-to-z

    Alpha-1 Antitrypsin Deficiency - Symptoms and Causes - Penn …

  6. People also ask
    What causes AAT deficiency?
    AAT deficiency is a genetic disorder. That means it's caused by changes in your genes, which may also be called gene variants or mutations. Your genes carry information that controls what you look like and how your body works. AAT deficiency is caused by changes in the SERPINA1 gene, which carries instructions for making the AAT protein.

    Alpha-1 Antitrypsin Deficiency - MedlinePlus

    medlineplus.gov
    What does it mean if someone has low tryptase levels during anaphylaxis?

    Dr. Shaheen Bin Hameed

    Doctor of Medicine (MBBS) · 9 years of exp

    In anaphylactic shock, raise in tryptase due to activation of mast cells. A low tryptase can be suggestive of a drug interaction such as in ADHD, a false negative value - a repeat sample can help to rule out it, responded anaphylactic shock to management.
    Q&A: Anaphylaxis
    bing.com
    What are the symptoms of AAT deficiency?
    Some people who have Alpha-1 Antitrypsin (AAT) deficiency may experience symptoms of COPD and respond well to asthma medicines. Rarely, AAT deficiency can cause skin problems, such as painful lumps or patches. Some people may also develop liver damage, with signs including jaundice and swelling in the legs.

    COPD - Alpha-1 Antitrypsin Deficiency | NHLBI, NIH

    nhlbi.nih.gov
    Where can I find information about AAT deficiency?
    More information about Alpha-1 Antitrypsin Deficiency is available from the Alpha-1 Foundation. They offer a nationwide network of affiliated support groups for alpha-1 patients and families. Communicate regularly with your doctors about changes in your breathing and general health.

    Treating and Managing Alpha-1 Antitrypsin Deficiency

    lung.org
    Can AAT deficiency lead to serious health issues?
    While many people with AAT deficiency can live a normal lifespan, especially if they avoid smoking, others may have serious complications. These can include lung disease and liver disease. Your medical outlook depends on several factors.

    Alpha-1 Antitrypsin (AAT) Deficiency - WebMD

    webmd.com
    What is the difference between a normal and a deficiency of AAT?
    Normal is associated with normal levels of AAT and its proper functioning. The group of normal alleles is referred to as M, and the typical genotype with normal AAT levels is MM. Deficient is associated with a deficiency in plasma AAT levels below 35% of the average normal level.

    Alpha-1 Antitrypsin Deficiency - StatPearls - NCBI Bookshelf

    ncbi.nlm.nih.gov
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  7. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov › books

    Alpha-1 Antitrypsin Deficiency - StatPearls - NCBI …

    Aug 17, 2024 · Alpha-1 antitrypsin (AAT) deficiency is a genetically inherited condition characterized by the impaired production of the alpha-1 antitrypsin protein. This protein protects the body from neutrophil elastase, an enzyme …

  8. MedlinePlus
    https://medlineplus.gov

    Alpha-1 Antitrypsin Deficiency - MedlinePlus

    May 3, 2024 · Alpha-1 antitrypsin deficiency (AAT deficiency, or AATD) is an inherited condition that raises your risk for lung and liver disease. If you have this condition, your body doesn't make enough alpha-1 antitrypsin (AAT).

  9. National Organization for Rare Disorders
    https://rarediseases.org › rare-diseases

    Alpha-1 Antitrypsin Deficiency - Symptoms, Causes, …

    Mar 21, 2024 · Alpha-1 antitrypsin deficiency (A1AT) is caused by disease-causing variants in the gene that is responsible for producing the alpha-1 antitrypsin protein.

  10. American Lung Association
    https://www.lung.org › ... › symptoms-diagnosis

    Alpha-1 Antitrypsin Deficiency Symptoms and Diagnosis

  11. eMedicine
    https://emedicine.medscape.com › article

    Alpha1-Antitrypsin (AAT) Deficiency - Medscape

  12. NHLBI, NIH
    https://www.nhlbi.nih.gov › resources

    What Is Alpha-1 Antitrypsin (AAT) Deficiency? Fact …

    Learn about alpha-1 antitrypsin deficiency, a genetic disorder that affects breathing and can cause COPD. Find out how to manage your condition, order free publications, and contact the NHLBI Center for Health Information.

  13. American Lung Association
    https://www.lung.org › lung-health-diseases › lung-disease-lookup

    Learn About Alpha-1 Antitrypsin Deficiency

  14. NHLBI, NIH
    https://www.nhlbi.nih.gov › ...
    [PDF]

    What Is Alpha-1 Antitrypsin (AAT) Deficiency? - NHLBI, NIH

  15. Cincinnati Children's Hospital Medical Center
    https://www.cincinnatichildrens.org › health › alpha

    Alpha-1 Antitrypsin Deficiency | Symptoms, Diagnosis & Treatment

  16. Columbia University Department of Surgery
    https://columbiasurgery.org › conditions-and-treatments

    Alpha-1 Antitrypsin Deficiency | Conditions and Treatments

  17. American Lung Association
    https://www.lung.org › ... › treating-and-managing

    Treating and Managing Alpha-1 Antitrypsin Deficiency

  18. The New England Journal of Medicine
    https://www.nejm.org › doi › full

    Alpha 1 -Antitrypsin Deficiency - The New England Journal of …

  19. Drugs.com
    https://www.drugs.com › cg

    Alpha-1 Antitrypsin Deficiency - What You Need to Know

  20. Patient
    https://patient.info › chest-lungs

    Alpha-1 Antitrypsin Deficiency: Symptoms and Treatment - Patient

  21. Kaiser Permanente
    https://healthy.kaiserpermanente.org › ...

    Alpha-1 Antitrypsin (AAT) Deficiency | Kaiser Permanente

  22. Rare Disease Advisor
    https://www.rarediseaseadvisor.com › news

    Alpha-1 Antitrypsin Deficiency Associated With Adverse Birth …