The 110 metres hurdles, or 110-metre hurdles, is a hurdling track and field event for men. It is included in the athletics programme at the Summer Olympic Games. The female counterpart is the 100 metres hurdles. As part of a racing event, ten hurdles of 42 inches (106.7 cm) in height are evenly spaced along a straight course of 110 metres.

The sprint hurdles at the Summer Olympics have been contested over a variety of distances at the multi-sport event. The men's 110 metres hurdles has been present on the Olympic athletics programme since the first edition in 1896. A men's 200 metres hurdles was also briefly held, from 1900 to 1904.