to come up with an educated guess based on prior knowledge or statistics Examples of Hypothesize in a sentence Scientists hypothesize that the Big Bang Theory was not actually caused by a giant meteor but ozone depletion.

to assume tentatively or set forth as a plausible explanation or as a reasonable basis for further investigation in the light of established facts: Given these data, we can hypothesize that the rise in truck accidents is directly related to the stressful work environment and unsafe driving practices of drivers.

Examples of hypothesize in a Sentence Psychologists hypothesized that his odd behavior was caused by a chemical imbalance in the brain. if we hypothesize that current population trends continue for the next 50 years