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  1. Nephrogenic diabetes insipidus (NDI) is caused by inability of the kidneys to concentrate urine by reabsorbing water in the collecting duct NDI can be inherited (X-linked or autosomal) or acquired, most commonly as a result of lithium treatment
    Author: Detlef Bockenhauer, Daniel G. Bichet
    Publish Year: 2015

    Pathophysiology, diagnosis and management of nephrogenic diab…

    www.nature.com/articles/nrneph.2015.89
    www.nature.com/articles/nrneph.2015.89
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    What causes nephrogenic diabetes insipidus?
    Other causes of acquired nephrogenic diabetes insipidus include hypokalemia (low blood potassium), post-obstructive polyuria, sickle cell disease or trait, amyloidosis, Sjögren syndrome, renal cystic disease, Bartter syndrome, and various medications ( amphotericin B, orlistat, ifosfamide, ofloxacin, cidofovir, vaptans ). [citation needed]

    Nephrogenic diabetes insipidus - Wikipedia

    en.wikipedia.org
    Can nephrotic syndrome and allergies be related?

    Dr. Yosuke Hirasawa

    Doctor of Medicine - MD · 11 years of exp

    Idiopathic nephrotic syndrome of unknown cause is frequently associated with asthma and urticaria, and the possibility of allergy involvement has been pointed out. There are reports that idiopathic nephrotic syndrome can be relieved by removing food allergens and inhaled antigens, so I think it is worth trying.
    Q&A: Nephrotic Syndrome
    bing.com
    Can nephrogenic diabetes insipidus be inherited?
    An inherited gene mutation. The hereditary form of nephrogenic diabetes insipidus can be caused by mutations in at least two genes. About 90% of hereditary nephrogenic diabetes insipidus cases are due to mutations in the AVPR2. Most of the remaining 10% of cases are due to mutations in the AQP2 gene.

    Diabetes Insipidus: Causes, Symptoms, Diagnosis & Treatment

    my.clevelandclinic.org
    How does nephrogenic diabetes insipidus affect the kidneys?
    In nephrogenic diabetes insipidus, enough ADH is produced. But the kidneys are partially or completely blind to it. Typically, the kidneys' ADH sensors are missing or defective. As a result, ADH no longer works as it should. The kidneys don't absorb enough water. Instead, they excrete abundant dilute urine as if little or no ADH were present.

    Nephrogenic Diabetes Insipidus: Treatments and More - WebMD

    webmd.com
    What causes autosomal dominant nephrogenic diabetes insipidus?
    Three families with autosomal dominant nephrogenic diabetes insipidus caused by aquaporin-2 mutations in the C-terminus. Am. J. Hum. Genet. 69, 738–748 (2001). Kamsteeg, E. J. et al. Reversed polarized delivery of an aquaporin-2 mutant causes dominant nephrogenic diabetes insipidus.

    Pathophysiology, diagnosis and management of nephrogenic diabetes i…

    nature.com
    What is nephrogenic diabetes insipidus (NDI)?
    Nephrogenic diabetes insipidus (NDI) is a rare disorder that occurs when the kidneys are unable to concentrate urine. In most people, the body balances the fluids you drink with the amount of urine you excrete, or expel, from your body. However, people with NDI produce excessive amounts of urine.

    Nephrogenic Diabetes Insipidus (NDI): What is it? - Healthline

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    Nephrogenic diabetes insipidus - Wikipedia

    Nephrogenic diabetes insipidus is caused by an improper response of the kidney to vasopressin, leading to a decrease in the ability of the kidney to concentrate the urine by removing free water. Signs and symptoms. See more

    Overview

    Nephrogenic diabetes insipidus, recently renamed arginine vasopressin resistance (AVP-R) and previously known as renal diabetes insipidus, is a form of diabetes insipidus primarily due to pathology of the kidney. … See more

    Diagnosis

    Differential diagnosis includes nephrogenic diabetes insipidus, neurogenic/central diabetes insipidus and psychogenic polydipsia. They may … See more

    Etymology

    The name of the disease comes from:
    • diabetes: from Latin: diabetes, from Ancient Greek: διαβήτης diabḗtēs "a passer-through; … See more

    Signs and symptoms

    The clinical manifestation is similar to neurogenic diabetes insipidus, presenting with polydipsia (excessive thirst) and polyuria (excretion … See more

    Causes

    Acquired
    Nephrogenic diabetes insipidus is most common in its acquired forms, meaning that the defect was … See more

    Treatment

    Persons with nephrogenic diabetes insipidus must consume enough fluids to equal the amount of urine produced. Any underlying cause … See more

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  4. Cleveland Clinic
    https://my.clevelandclinic.org/health/diseases/...

    Nephrogenic Diabetes Insipidus: Symptoms & Treatment

  5. Cleveland Clinic
    https://my.clevelandclinic.org/health/diseases/16618

    Diabetes Insipidus: Causes, Symptoms, Diagnosis & Treatment

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    Nephrogenic diabetes insipidus
    Diabetes mellitus
    Causes of Diabetes Insipidus.
  7. WebMD
    https://www.webmd.com/diabetes/nephrogenic...

    Nephrogenic Diabetes Insipidus: Treatments and More - WebMD

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    Nephrogenic Diabetes Insipidus
    Causes of Diabetes Insipidus.
  8. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Diabetes insipidus - Symptoms and causes - Mayo Clinic

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    Diabetes Insipidus Symptoms
    Mayo Clinic
  9. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/books/NBK470458

    Arginine Vasopressin Disorder (Diabetes Insipidus)

    Jan 11, 2024 · The hallmarks of diabetes insipidus (DI) include polyuria (>50 mL/kg), dilute urine (osmolality <300 mOsm/L), and increased thirst with the intake of up to 20 L/day fluid intake.[2] Untreated DI can cause hypovolemia, …

    Tags:
    Diabetes mellitus
    Diabetes Insipidus Untreated
    Published:2024/01/11
  10. nih.gov
    https://www.niddk.nih.gov/.../diabetes-i…

    Diabetes Insipidus - NIDDK - National Institute of …

    Nephrogenic diabetes insipidus. In nephrogenic diabetes insipidus, your body makes enough vasopressin but your kidneys don’t respond to the hormone as they should. As a result, too much fluid gets flushed out in your urine. Causes …

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    Nephrogenic diabetes insipidus
    Diabetes mellitus
    Causes of Diabetes Insipidus.
  11. UpToDate
    https://www.uptodate.com/contents/clinical...

    Arginine vasopressin resistance (nephrogenic diabetes insipidus ...

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    ADH
  12. Everyday Health
    https://www.everydayhealth.com/diabetes/diabetes-insipidus

    Diabetes Insipidus: Symptoms, Causes, Diagnosis, Treatment, …

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    Diabetes mellitus
    Diabetes Insipidus Symptoms
  13. Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/...

    Diabetes insipidus - Diagnosis and treatment - Mayo Clinic

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    Mayo Clinic
  14. WebMD
    https://www.webmd.com/diabetes/what-is-diabetes-insipidus

    Diabetes Insipidus (DI): Symptoms, Causes, Diagnosis, and …

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    Nephrogenic diabetes insipidus
    Diabetes mellitus
    Causes of Diabetes Insipidus.
  15. UpToDate
    https://www.uptodate.com/contents/arginine...

    Arginine vasopressin resistance (nephrogenic diabetes insipidus ...

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    Argipressin
  16. Healthline
    https://www.healthline.com/health/diabetes-insipidus-nephrogenic

    Nephrogenic Diabetes Insipidus (NDI): What is it? - Healthline

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    Nephrogenic Diabetes Insipidus
    Ndi Diabetes
    Inability To Concentrate Urine
  17. Nature
    https://www.nature.com/articles/s41572-019-0103-2

    Diabetes insipidus | Nature Reviews Disease Primers

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    Diabetes Insipidus Wikem
    Diabetes Insipidus Mechanism
    Diabetes Insipidus Review
  18. Nature
    https://www.nature.com/articles/nrneph.2015.89

    Pathophysiology, diagnosis and management of nephrogenic …

    Tags:
    Nephrogenic diabetes insipidus
    Ndi Diabetes
    Inability To Concentrate Urine
  19. NHS
    https://www.nhs.uk/conditions/diabetes-insipidus

    Diabetes insipidus - NHS

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    ADH
    Diabetes insipidus
  20. nih.gov
    https://www.niddk.nih.gov/.../insipidus_508.pdf
    [PDF]

    Diabetes Insipidus - National Institute of Diabetes and …

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    Diabetes mellitus
    Diabetes Insipidus Pathophysiology
    Diabetes Insipidus Type 1 Or 2
  21. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138272

    Nephrogenic diabetes insipidus in children (Review) - PMC

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    Ndi Diabetes
    Diabetes Insipidus Review
    Indomethacin Diabetes Insipidus
  22. Geeky Medics
    https://geekymedics.com/di

    Diabetes Insipidus - Geeky Medics

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    Diabetes mellitus
    Diabetes Insipidus Mechanism
    Diabetes Insipidus Wikem
  23. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610677

    Nephrogenic Diabetes Insipidus: Essential Insights into the …

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    Nephrogenic diabetes insipidus
    Publish Year:2013
    Published:2013/04
  24. Genetic and Rare Diseases Information Center
    https://rarediseases.info.nih.gov/diseases/7178/...

    Nephrogenic diabetes insipidus | About the Disease | GARD

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    Nephrogenic diabetes insipidus
    Causes of Diabetes Insipidus.
  25. ERKNet
    https://www.erknet.org/guidelines-pathways/...

    Nephrogenic Diabetes Insipidus - erknet.org

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    Statement
  26. Nature
    https://www.nature.com/articles/s41581-024-00897-z

    International expert consensus statement on the diagnosis and ...

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    Ndi Diabetes