Options include terbinafine, clotrimazole, miconazole, or econazole cream. Treatment with a topical antifungal cream may be repeated in the future if there is a good response to topical treatment and there are recurrent episodes of mild, non-extensive disease.

Topical antifungals used for intertrigo are nystatin (for Candida) and azole drugs, including miconazole (Mitrazol), ketoconazole (Nizoral topical), or clotrimazole (Lotrimin AF cream). You usually use the cream twice a day for 2 to 4 weeks.