Clinical efficacy and safety: anti-infectives for systemic use The European Medicines Agency's scientific guidelines on the clinical evaluation of human medicines used to treat or prevent …

Here we provide an overview of the major preventative and therapeutic uses for topical agents and a review of the clinical and molecular epidemiology of resistance to these agents. …

Oct 12, 2024 · Antibacterial agents are intended to treat or prevent various bacterial infections. They are of major importance to public health as bacterial infections may be potentially life …

Background: Concerns have recently emerged about the efficacy and the quality of antibacterial generic products approved for use in humans. Methods: We searched Medline and Embase …

Sep 29, 2016 · 1. Introduction 2. Antibiotic Resistance 3. Individual Antibiotics 3.1. J01A Tetracyclines 3.2. J01B Amphenicols 3.3. J01C β-Lactam Antibacterials, Penicillins 3.4. J01D …

4 days ago · Antibacterial resistance is a global challenge that requires a coordinated international response. The current clinical pipeline largely consists of derivatives of established antibiotic …

Penicillins G and V are recommended for classical erysipelas (caused by hemolytic streptococci). For uncomplicated soft tissue infections originating from wounds, which are mostly due to …

WHO analysed the pipeline of antibacterial products (antibiotics and biologicals) that were in phase I-III of clinical development (from 1 July 2017 to 31 December 2023) and which had not, …

Antimicrobial peptide research remains active not only because of the growing antibiotic resistance problem but also our desire to understand the role of innate immune peptides in …

Mar 9, 2020 · There is a continued need for innovation and new-class antibacterial agents in order to provide effective therapeutic options against infections specifically caused by XDR and PDR …

The purpose of this guidance is to assist sponsors in the development, analysis, and presentation of microbiology data during antibacterial drug development.

A topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria. Ganciclovir: A DNA polymerase inhibitor used to treat cytomegalovirus …

WHO analysed the pipeline of antibacterial products (antibiotics and biologicals) that were in phase I-III of clinical development (as of September 2020) and which had not, at that date, …

Explore our directory of antibacterials for systemic use companies, products and news. Easily search thousands of antibacterials for systemic use products and active suppliers.

Feb 6, 2003 · The Food and Drug Administration (FDA) is amending its regulations to require that the labeling for all systemic antibacterial drug products (i.e., antibiotics and their synthetic …

WHO analysed the pipeline of antibacterial products (antibiotics and biologicals) that were in phase I-III of clinical development (as of September 2019) and which had not, at that date, …

Mar 21, 2025 · Key Points. Question Are 7 days of antibiotic therapy adequate for the treatment of most Gram-negative bloodstream infections?. Findings In this systematic review and meta …

4 days ago · If CDAD is suspected or confirmed, ongoing antibacterial drug use not directed against C difficile may need to be discontinued; Institute appropriate fluid and electrolyte …

Systemic antibacterials have been used in the treatment of acne for many years, and there are several commonly used antibacterials which have established efficacy and safety records.

Mar 7, 2025 · Antibiotic resistance is currently one of the most significant threats to global public health and safety. And studies have found that over the next 25 years, 39 million people will …