It was announced that Aguero was dealing with arrhythmia, also known as an irregular heart rhythm. The club ruled him out for three months following a cardiac exam. He has since undergone regular cardiac exams with the results indicating it was time for him to hang up his cleats.

Barcelona confirmed that Aguero was suffering from arrhythmia, which is associated with improper beating of the heart, whether irregular, too fast or too slow. Since then, the forward had undergone regular cardiac exams to monitor his well-being before the doctors came to a conclusion that it is better he cuts his career short.