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See all on WikipediaMyokine - Wikipedia
A myokine is one of several hundred cytokines or other small proteins (~5–20 kDa) and proteoglycan peptides that are produced and released by skeletal muscle cells (muscle fibers) in response to muscular contractions. They have autocrine, paracrine and/or endocrine effects; their systemic effects occur at … See more
The definition and use of the term myokine first occurred in 2003. In 2008, the first myokine, myostatin, was identified. The gp130 receptor cytokine IL-6 (Interleukin 6) was the first … See more
In repetitive skeletal muscle contractions
There is an emerging understanding of skeletal muscle as a secretory organ, and of myokines as … See moreMyostatin
Both aerobic exercise and strength training (resistance exercise) attenuate myostatin expression, and myostatin inactivation potentiates the beneficial effects of endurance exercise on metabolism. See more2003The definition and use of the term myokine first occurred.2008The first myokine, myostatin, was identified.2002FNDC5 was initially discovered.2012-12-14Boström et al. reported that exogenous irisin may aid in heightening energy expenditure, and thus in reducing obesity.2014-07-01Kanzleiter et al. established that decorin is secreted during muscular contraction against resistance, and plays a role in muscle growth."Some myokines exert their effects within the muscle itself. Thus, myostatin, LIF, IL-6 and IL-7 are involved in muscle hypertrophy and … See more
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1. ^ Cite error: The named reference :0 was invoked but never defined (see the help page See moreWikipedia text under CC-BY-SA license Role of Myokines in Regulating Skeletal Muscle Mass and Function
Jan 30, 2019 · Myokines are cytokines or peptides synthesized and released by myocytes in muscle tissue in response to muscular contractions (Pedersen et al., 2007). The term …
Interleukin 6 - Wikipedia
IL-6 is also considered a myokine, a cytokine produced from muscle, which is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. During exercise, it is thought to act in a hormone-like manner to mobilize extracellular substrates and/or augment substrate delivery.
Like in humans, there seems to be an increase in IL-6 expression in working muscle and plasm…Wikipedia · Text under CC-BY-SA license- Estimated Reading Time: 10 mins
- Studies of Myokine wikipedia
Muscle–Organ Crosstalk: The Emerging Roles of Myokines
May 11, 2020 · Recent advances show that skeletal muscle produces myokines in response to exercise, which allow for crosstalk between the muscle and other organs, including brain, …
Why Are Myokines Called 'Hope Molecules'?
Jun 30, 2023 · Learn how proteins released by muscle contraction, called myokines or "hope molecules," could make us more resilient to stress.
Mechanisms by Which Skeletal Muscle Myokines Ameliorate …
Apr 22, 2022 · Skeletal muscle is vital for metabolism and physiology and plays a crucial role in insulin-mediated glucose disposal. Myokines have autocrine, paracrine, and endocrine …
Interleukin 6 - wikidoc
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. [1] In addition, osteoblasts …
Myokines - Vocab, Definition, and Must Know Facts | Fiveable
Myokines are signaling molecules produced and released by muscle cells in response to muscle contraction. They play a crucial role in intercellular communication, influencing metabolic …
Myokine - Wikiwand
A myokine is one of several hundred cytokines or other small proteins (~5–20 kDa) and proteoglycan peptides that are produced and released by skeletal muscle cells (muscle fibers) …
Osteocrin, a novel myokine, prevents diabetic cardiomyopathy via ...
Jun 16, 2021 · Osteocrin (OSTN) acts as a novel exercise-responsive myokine and is implicated in various cardiac diseases. Herein, we aim to investigate the role and underlying molecular …
Myokine - Wikiwand
A myokine is one of several hundred cytokines or other small proteins and proteoglycan peptides that are produced and released by skeletal muscle cells in response to muscular contractions.
Acta Physiologica - Wiley Online Library
Aug 23, 2019 · Myokines are molecules produced and secreted by skeletal muscle to act in an auto-, para- and endocrine manner to alter physiological function of target tissues.
Myokine – Wikipedia
Myokine sind hormonähnliche Botenstoffe, die von der Muskulatur der Säugetiere bei Bewegung und Kontraktion ausgeschüttet werden. Der Name leitet sich aus dem griechischen „Mys“: …
Myostatin - Wikipedia
Myostatin is a myokine that is produced and released by myocytes and acts on muscle cells to inhibit muscle growth. [7] Myostatin is a secreted growth differentiation factor that is a member …
Role of Myokines in Regulating Skeletal Muscle Mass and Function
Jan 29, 2019 · Myokines are cytokines or peptides synthesized and released by myocytes in muscle tissue in response to muscular contractions (Pedersen et al., 2007). The term …
Myokine — Wikipédia
Les myokines sont des cytokines, des substances solubles de signalisation cellulaire synthétisées par les myocytes, les cellules constitutives des muscles. Elles sont produites lors de l' activité …
Myosin - Wikipedia
Myosins (/ ˈmaɪəsɪn, - oʊ -/ [ 1 ][ 2 ]) are a family of motor proteins best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes. They are …
Cytokine - Wikipedia
Cytokines are important in health and disease, specifically in host immune responses to infection, inflammation, trauma, sepsis, cancer, and reproduction. The word comes from the ancient …
myokine - Wiktionary, the free dictionary
Aug 19, 2024 · myokine (plural myokines) (biochemistry) A form of cytokine produced in muscle cells.
FNDC5 - Wikipedia
The FNDC5 gene encodes a prohormone, a single-pass type I membrane protein (human, 212 amino acids; mouse and rat, 209 amino acids) that is upregulated by muscular exercise and …
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