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  1. Definition

    One single gene has the ability to produce multiple proteins that differ both in structure and composition; this process … See more

    Protein isoform - Wikipedia

    • A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences. While many perform the same or similar biological roles, some isoforms have unique functions. A set of protein isoforms may be formed from alternative splicings, variable promoter usag… See more

    Mechanism

    The primary mechanisms that produce protein isoforms are alternative splicing and variable promoter usage, though modifications due to genetic changes, such as mutations and polymorphisms are sometimes … See more

    Characteristics

    Generally, one protein isoform is labeled as the canonical sequence based on criteria such as its prevalence and similarity to orthologous—or functionally analogous—sequences in other species. Isoforms ar… See more

    Related concepts

    A glycoform is an isoform of a protein that differs only with respect to the number or type of attached glycan. Glycoproteins often consist of a number of different glycoforms, with alterations in the attached saccharide or oligosacch… See more

    Examples

    G-actin: despite its conserved nature, it has a varying number of isoforms (at least six in mammals).
    Creatine kinase, the presence of which in the blood can be used as an aid in the diagnosis of myocardial infarction, … See more

     
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  1. Protein isoform - Wikiwand

     
  2. Isozyme - Wikipedia

  3. What are the differences between isozymes, allozymes and …

  4. Isoforms: Fundamental differences - eLife

  5. Protein isoforms: more than meets the eye | Nature Methods

  6. The human proteome in isoform - The Human Protein Atlas

  7. Isoforms Definition & Meaning - Merriam-Webster

  8. isoforms and the definition of a protein - Biostar: S

  9. ROSALIND | Glossary | Protein isoform

    A protein isoform is one of a number of different structurally similar proteins that are created as the result of alternative splicing or from similar genes formed from a copied gene and differentiated as the result of evolution.

  10. Analysis of protein isoforms: can we do it better? - PMC

  11. Protein Isoform - an overview | ScienceDirect Topics

  12. Alternative splicing - Wikipedia

  13. isoform - Wiktionary, the free dictionary

  14. Fundamental differences - PMC - National Center for …

  15. The Actin Gene Family: Function Follows Isoform - PMC

  16. Isotype (immunology) - Wikipedia

  17. アイソフォーム - Wikipedia