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  1. Actin - Wikipedia

    • Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where it may be present at a concentration of over 100 ÎĽM; its mass is roughly 42 kDa, with a diameter of 4 to 7 nm. An actin protein is the monomeric subunit of two types of filament… See more

    SymbolActin
    InterProIPR004000
    PROSITEPDOC00340
    Function

    Actin's primary role in the cell is to form linear polymers called microfilaments that serve various functions in the cell's structure, trafficking networks, migration, and replication. The multifaceted role of actin relies … See more

    Structure

    Monomeric actin, or G-actin, has a globular structure consisting of two lobes separated by a deep cleft. The bottom of the cleft represents the "ATPase fold", a structure conserved among ATP and GTP-binding proteins th… See more

    Assembly dynamics

    Actin filaments are often rapidly assembled and disassembled, allowing them to generate force and support cell movement. Assembly classically occurs in three steps. First, the "nucleation phase", in which two to three G-… See more

     
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  1. Family of globular multi-functional proteins

    Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where it may be present at a concentration of over 100 ÎĽM; its mass is roughly 42 kDa, with a diameter of 4 to 7 nm.
    en.wikipedia.org/wiki/Actin
    en.wikipedia.org/wiki/Actin
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  4. Actin | Definition & Function | Britannica

    actin, protein that is an important contributor to the contractile property of muscle and other cells. It exists in two forms: G-actin (monomeric globular actin) and F-actin (polymeric fibrous actin), the form involved in muscle contraction.

  5. Origins and Evolution of the Actin Cytoskeleton

    Actin is a remarkably conserved protein, with overall identity about 85% between the most divergent family members. However, most species possess multiple actin isoforms exhibiting both structural and functional differences. The …

  6. Cell - Actin Filaments, Cytoskeleton, Proteins | Britannica

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  8. Structure and Organization of Actin Filaments - The Cell

    Within the cell, actin filaments (also called microfilaments) are organized into higher-order structures, forming bundles or three-dimensional networks with the properties of semisolid gels.

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  13. Actin: Anatomy and function - Kenhub

    Oct 30, 2023 · Actin is the major protein constituent of the cytoskeleton of eukaryotic cells. Find out more about its anatomy and function at Kenhub!

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